Note: If your company does not use Microsoft Exchange, you cannot set an auto response message directly within Outlook. If you complete the first step of these instructions and you do not find Out of Office Assistant listed in the Tools menu, then your Outlook is not using Microsoft Exchange to access email. You will need to set an auto response message through your webmail tool, as it is usually provided there. Instructions for some popular webmail providers: Gmail, Yahoo, Hotmail/Windows Live, Comcast
